Exportal^®

Exportal^®

helps eliminate constipation and restore intestinal barrier function to protect the entire body from endotoxin aggression^1,2.

The active substance is lactitol, belongs to the group of osmotic laxatives recommended by the Russian Gastroenterological Association and the Society of Pediatric Gastroenterologists, Nutritionists and Hepatologists as first–line medications for the medical treatment of constipation^1,2.

Lactitol attracts and retains water in the lumen of the colon. As a result, the contents of the colon are softened to facilitate bowel movements¹.

Subsequently, lactitol is processed by bacteria that are useful for the human body, living in the colon, with the formation of a large amount of butyric acid. Butyric acid "nourishes" intestinal cells, which helps restore its barrier function to protect the body from the penetration of bacteria and their components (for example, endotoxins) from the intestinal lumen^2,3.

In addition, lactitol "nourishes" the bacteria of the colon that are useful for the human body, thus restoring the microbiome (the prebiotic effect of lactitol, similar to the action of dietary fiber)¹.

Advantages of Exportal^®1:

• Does not contain auxiliary substances, dyes and flavors;
• It tastes similar to table sugar, but less sweet;
• Packaged in sachets, which are convenient to take with you;
• It works only in the intestinal lumen;

Exportal^® can be applied¹:

• children over 1 year old;
• pregnant and lactating women (if the potential benefit to the mother exceeds the potential risk to the fetus and child);
• patients with diabetes mellitus, because lactitol does not increase blood glucose levels;
• patients with liver diseases;
• elderly people.

The method of application of Exportal^{® 1}:

1 time a day, inside during meals, mixed with various drinks (water, tea, coffee, juices, etc.) or liquid food.

¹IMP Exportal LSR-003898/07

²Ardatskaya M. D. et al . Clinical and metabolic efficacy of lactitol in the treatment of chronic constipation (results of a non-interventional prospective observational program "OSMOAID") //Experimental and clinical gastroenterology. – 2018. – №. 2 (150).

³Ivashkin V. T. et al . Diagnosis and treatment of constipation in adults (Clinical recommendations of the Russian Gastroenterological Association and the Association of Coloproctologists of Russia) //Russian Journal of Gastroenterology, Hepatology, Coloproctology. – 2020. – Vol. 30. – No. 6. – pp. 69-85.

⁴Belmer S. V. et al. Functional disorders of the digestive organs in children. Recommendations of the Society of Pediatric Gastroenterologists, Hepatologists and Nutritionists. Part 2 //Russian Bulletin of Perinatology and Pediatrics. – 2020. – Vol. 65. – No. 5.